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Patient guide · Advanced Endocrinology · 1 min read

Phaeochromocytoma & Paraganglioma

Answers to common questions about phaeochromocytoma & paraganglioma.

Questions on this page
  1. What is a phaeochromocytoma?
  2. What symptoms can it cause?
  3. What is a paraganglioma?
  4. Can these tumours be genetic?
  5. Why is genetic evaluation important?

What is a phaeochromocytoma?

A phaeochromocytoma is a rare tumour arising from adrenal chromaffin cells that can produce excess catecholamines.

What symptoms can it cause?

Possible symptoms include:

  • Episodic headaches
  • Sweating
  • Palpitations
  • Tremor
  • High blood pressure

What is a paraganglioma?

A paraganglioma is a related neuroendocrine tumour arising outside the adrenal gland.

Can these tumours be genetic?

Yes. A significant proportion of phaeochromocytomas and paragangliomas are associated with hereditary syndromes or genetic variants.

Why is genetic evaluation important?

Identifying a hereditary cause may influence treatment, surveillance and screening of family members.

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