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Patient guide · Endocrine Emergencies · 1 min read

Hyperglycaemic Hyperosmolar State – HHS

Answers to common questions about hyperglycaemic hyperosmolar state – hhs.

Questions on this page
  1. What is HHS?
  2. Who is more likely to develop HHS?
  3. What are the symptoms?
  4. Is HHS an emergency?
  5. What can trigger HHS?

What is HHS?

Hyperglycaemic hyperosmolar state is a serious diabetes emergency characterized by very high blood glucose, severe dehydration and increased blood osmolality, usually without the marked ketoacidosis seen in DKA.

Who is more likely to develop HHS?

It is more commonly seen in people with type 2 diabetes, particularly older adults, although it can occur in other situations.

What are the symptoms?

Possible symptoms include:

  • Extreme thirst
  • Frequent urination
  • Severe dehydration
  • Weakness
  • Confusion
  • Drowsiness
  • Altered consciousness

Is HHS an emergency?

Yes. Suspected HHS requires immediate medical evaluation and usually inpatient treatment.

What can trigger HHS?

Possible triggers include:

  • Infection
  • Heart attack
  • Stroke
  • Other acute illnesses
  • Inadequate diabetes treatment
  • Severe dehydration
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