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Patient guide · Adrenal Disorders · 1 min read

Adrenal Tests

Answers to common questions about adrenal tests.

Questions on this page
  1. What is an 8 AM cortisol test?
  2. What is an ACTH stimulation test?
  3. What is ACTH?
  4. What is the aldosterone-renin ratio?
  5. What tests are used for phaeochromocytoma?
  6. Why can't adrenal hormone reports be interpreted in isolation?

What is an 8 AM cortisol test?

Cortisol normally follows a daily rhythm and is usually highest in the morning. An early-morning cortisol measurement can help evaluate possible adrenal insufficiency in appropriate clinical settings.

What is an ACTH stimulation test?

This test evaluates how the adrenal glands respond to ACTH and is commonly used when adrenal insufficiency needs further evaluation.

What is ACTH?

ACTH is a pituitary hormone that stimulates the adrenal glands to produce cortisol.

What is the aldosterone-renin ratio?

It is a screening test used when primary aldosteronism is suspected.

What tests are used for phaeochromocytoma?

Testing may involve plasma or urinary metanephrines, depending on the clinical situation.

Why can't adrenal hormone reports be interpreted in isolation?

Hormone levels can be influenced by:

  • Time of day
  • Medications
  • Stress
  • Acute illness
  • Posture
  • Sodium intake
  • Other hormonal conditions

The result must therefore be interpreted in the appropriate clinical context.

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