MODY – Maturity-Onset Diabetes of the Young
Answers to common questions about mody – maturity-onset diabetes of the young.
Questions on this page
What is MODY?
MODY is a group of inherited forms of diabetes caused by specific genetic changes that affect pancreatic beta-cell function.
Is MODY the same as type 1 diabetes?
No. MODY is genetically different from type 1 diabetes and usually does not result from autoimmune destruction of beta cells.
Is MODY the same as type 2 diabetes?
No. MODY is caused by a single-gene change, whereas type 2 diabetes is a complex condition influenced by multiple genetic and environmental factors.
At what age does MODY occur?
MODY typically develops at a young age, often in adolescence or early adulthood, although the age of diagnosis can vary.
When should MODY be suspected?
It may be considered when diabetes occurs at a young age, particularly when there is:
- Diabetes in several successive generations
- Diabetes without typical features of type 1 diabetes
- Absence of pancreatic autoantibodies
- Preserved insulin production
- A pattern of diabetes that does not fit typical type 1 or type 2 diabetes
Why is diagnosing MODY important?
Different forms of MODY can respond differently to treatment. A correct genetic diagnosis may allow more appropriate treatment and can provide useful information for family members.
Can MODY be treated?
Yes. Treatment depends on the specific genetic subtype.
Can MODY be inherited?
Yes. Many forms of MODY follow an autosomal dominant inheritance pattern, meaning an affected person may have a significant chance of passing the genetic change to a child.
Should family members be tested?
Depending on the genetic diagnosis, testing may be appropriate for selected family members.