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Patient guide · Rare & Genetic Endocrine Disorders · 1 min read

Genetic Endocrine Tumour Syndromes

Answers to common questions about genetic endocrine tumour syndromes.

Questions on this page
  1. Can endocrine tumours be inherited?
  2. Which endocrine tumours can have genetic causes?
  3. When should an endocrine tumour raise suspicion of a genetic syndrome?

Can endocrine tumours be inherited?

Some endocrine tumours have hereditary forms.

Which endocrine tumours can have genetic causes?

Examples include:

  • Medullary thyroid carcinoma
  • Phaeochromocytoma
  • Paraganglioma
  • Parathyroid tumours
  • Pituitary tumours
  • Pancreatic neuroendocrine tumours

When should an endocrine tumour raise suspicion of a genetic syndrome?

Consideration may be appropriate when there is:

  • Young age at diagnosis
  • Multiple endocrine tumours
  • Bilateral or multifocal disease
  • Several affected relatives
  • Multiple primary tumours
  • A tumour type known to have hereditary forms
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