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Patient guide · Understanding Endocrine Tests · 1 min read

Prolactin

Answers to common questions about prolactin.

Questions on this page
  1. What is prolactin?
  2. What causes high prolactin?
  3. Can stress increase prolactin?
  4. Does high prolactin always mean a pituitary tumour?
  5. What is macroprolactin?

What is prolactin?

Prolactin is a pituitary hormone involved primarily in breast development and milk production.

What causes high prolactin?

Possible causes include:

  • Pregnancy
  • Breastfeeding
  • Certain medications
  • Hypothyroidism
  • Stress
  • Pituitary tumours such as prolactinoma
  • Kidney or liver disease

Can stress increase prolactin?

Yes. Prolactin can rise transiently in response to stress and other physiological factors.

Does high prolactin always mean a pituitary tumour?

No.

The cause must be evaluated before concluding that a pituitary tumour is present.

What is macroprolactin?

Macroprolactin is a form of prolactin that may be biologically less active but can contribute to an elevated laboratory prolactin result.

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